Peripheral artery disease (PAD) is a common condition in which fatty plaque builds up in the arteries. The plaque can harden and reduce the flow of blood to the head, organs, or limbs.
Although PAD can occur in any blood vessel in the body, it typically affects the legs, ankles and feet. When blood flow is reduced, patients with PAD may experience uncomfortable symptoms such as leg pain while walking (claudication), reduced pulse, skin temperature changes and pain at rest.1
Over time, the progressive disease can reduce quality of life and mobility. Critical limb ischemia (CLI) is the advanced stage of PAD that may lead to non-healing wounds below the ankle, gangrene and ultimately limb amputation, as well as other serious health complications.2 Patients with PAD are also at risk for the development of stroke and heart attack.3
Learn more about the signs and symptoms of PAD.